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The evidence: Varenicline is the most effective pharmacotherapy we have for smoking cessation
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This creates a significant 60-70% cost advantage for refillable systems on a per-use basis, a pricing dynamic that propelled open-system sales to a 34% year-on-year increase in 2025 [3]Source: Indonesian Ministry of Finance, Cukai Regulation for E-Liquids, customs.go.id
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This includes brushing twice daily with fluoride toothpaste, flossing every day to control plaque, limiting dark foods and drinks, and staying well hydrated to encourage healthy saliva flow
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