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However, the 2021 US Preventive Services Task Force concluded that the evidence was insufficient to assess the benefits and harms of pharmacologic therapy for tobacco cessation in pregnant women (see Tobacco Smoking Cessation in Adults, Including Pregnant Women: Behavioral and Pharmacotherapy Interventions)

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The most commonly reported symptoms include: Coughing Chest pain Burping or belching Bloating Difficulty swallowing Vomiting and regurgitation Sore throat Heartburn Nausea Sour taste of acid in the mouth Bad breath Excess amounts of saliva Difficulty sleeping after eating Many people experience mild symptoms of acid reflux on an occasional basis

(Benowitz et al., 2003) demonstrated a 24% acceleration in chlorzoxazone metabolism in smokers, highlighting the enzymes induction through smoking

This can cause head and neck cancer and cancers of the stomach, digestive tract and bladder as well