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And she kind of says whatever she thinks, and she's impulsive and a little bit toxic, and all of that could be easily played as more of a caricature

youth who used e-cigarettes preferred flavored options, with 88.2% of high school students and 85.7% of middle school students reporting use

PLoS ONE 10 , e0138182

Another study assessing vascular pathomechanisms indicated a 10 to 20-fold lower effect of IQOS compared to CS on the adhesion of monocytic cells on human coronary arterial endothelial cells (a surrogate of atherogenesis) 66

In addition to the technological hurdles they faced, industry lawyers had grown increasingly wary about the research, and the concession, implicit in such research, that existing cigarettes weren't safe