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These compounds are known to cause DNA damage, and have been strongly associated with bladder cancer [26]

These differences can be explained, in part, by the varying survey methodologies, the types of surveys administered, and the definitions of current smoking that are used

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Furthermore, the tobacco gas phase increases reactive oxygen species (ROS) in human umbilical vein endothelial cells (HUVECs), and inhibits thromboxane A2, thereby affecting platelet aggregation [6, 7]

1 and 2 for males and females respectively