Has the applicant demonstrated that the following statement in their proposed modified risk labeling and advertising is true: Scientific studies have shown that switching completely from cigarettes to the IQOS system significantly reduces your bodys exposure to harmful or potentially harmful chemicals.
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This marks the first time that marijuana use has eclipsed cigarette smoking and has raised concerns amongst prevention, enforcement and rehabilitation groups across the country
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Cardiovascular Risk Marijuana use, mechanistically due to an increase in catecholamines, cardiac workload, and carboxyhemoglobin levels as well as episodes of significant postural hypotension, may trigger an increase in the risk of myocardial infarction, especially in older patients at risk for cardiovascular disease
