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Except for this, combined with our findings that nicotine exposure significantly reduces the expression of transition proteins and protamines, interestingly, similar variations were detected in the bisphenol A-exposed testes, with inference of histone-to-protamine transition and DNA hypermethylation in spermatozoa 48

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One more difference between tobacco and cannabis is that tobacco products are made from the leaves of the plant, while cannabis products are made from the buds or flower of the plant

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