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Cessation using e-cigarettes may also lead to dual use of e-cigarettes and tobacco smoking (6% at 6 months in 1 trial28 and 25% at 1 year in another73), meaning that people will continue to be harmed by smoking

For example, compounds present in e-cigarette aerosols can lead to the generation of reactive oxygen species (ROS) and the creation of reactive intermediates that can bind to and damage DNA

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Elsevier for the American College of Cardiology: 10301045

The preclinical study involved both in vivo models and in vitro cultures of human cells, which were exposed to filtered air, nicotine aerosols or CBD aerosols for two weeks