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Furthermore, in an animal study, nicotine was shown to promote tumor growth, mainly by activating the -adrenoceptors and the subsequent expression of cyclooxygenase-2, prostaglandin E2, and VEGF in tumor tissues (79)

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[1] A 2004 series of monographs released by the International Agency for Research on Cancer, a part of the World Health Organisation, summarized research from the 1960s onwards about the carcinogenicity of tobacco on various laboratory animals

The song was widely recorded by other artists and became a hit for Peter, Paul, and Mary