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A systematic review evaluating 19 studies from 1966 to 2006 found no significant tobacco-adjusted association between cannabis smoking and lung cancer development despite evidence of precancerous histopathologic changes of the respiratory mucosa

This could be up to 36mg of nicotine, which would be equal to about 150% of nicotine to that of a tobacco cigarette

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This approach assumes that, in a perfect society, smokers would also pay the costs related to the harmful smoke that tobacco releases into the air