However, the study faced limitations, such as a small sample size, which diminished its power to detect abnormalities or significant changes over time, the potential for selection bias (as the study may have disproportionately included healthier e-cigarette users), and a medium-term follow-up duration
Chimerism or nonself cells may play a role in the pathogenesis of morphea by initiating a local inflammatory reaction.19 Clinical Findings Morphea is currently divided into five subtypes (Table 64-1).20 Superficial or deep disease (involving subcutis, fascia, or below) may occur with any subtype
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