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For cancer caused by smoking, common biomarkers are carcinogens bound to specific sections of DNA, called DNA adducts (see Section 3.3.2)

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To further verify this hypothesis, we used cholesterol-depleting agent methyl-beta-cyclodextrin (MCD) and agonist GW3965 to reduce excess intracellular cholesterol, and detected CSE-induced secretion of inflammatory factor IL6 in HBE cells using qPCR