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This means that consuming nicotine, through either a cigarette or a vape pen, can cause dehydration that leads to increased thirst

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Smoking complicates this management process by interfering with medication effectiveness, increasing insulin resistance, and undermining efforts to maintain stable blood sugar levels

The reasons for this are unclear but involve: Vascoconstriction and lack of oxygen reaching skin cells Delayed migration of keratinocytes Decreased collagen synthesis Delayed growth of new blood vessels within the wound