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Adding cannabis to a regimen that already includes other antidepressants, tramadol, triptans, or stimulants creates a more complex and potentially unsafe pharmacologic environment

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Compared to non-smokers, men who were continuous-smokers (odds ratio [OR] = 1.74, 95% confidence interval [CI] = 1.272.38) and past-smokers (OR = 1.47, 95% CI = 1.032.09) were at an increased risk of insulin resistance

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