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Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog

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Commenting broadly on vaping, he continued: "These studies call into question this assertion of certainty about the safety of electronic cigarettes" and leave experts in a "quandary about how to advise tobacco cigarette smokers." Asked whether vaping is as bad or worse for the heart as regular tobacco smoking, he said: "There is so little information about the long-term health effects of electronic cigarette use, including cardiovascular disease, and such a wealth of information about the serious adverse cardiovascular disease caused by tobacco smoking, that right now we would say tobacco smoking is more harmful than electronic cigarette use." "But these new studies give us reason to think that with enough time we may start seeing similar cardiovascular effects from chronic electronic cigarette use as we had seen from traditional cigarette use

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Weber AM et al